Evaluating systemic immune-inflammation index for in-hospital and long-term mortality in elderly non-ST elevation myocardial infarction patients

Abstract Introduction This investigation aimed to evaluate the predictive value of systemic immune-inflammation index (SII) for in-hospital and long-term mortality in elderly patients with non-ST elevation myocardial infarction (NSTEMI). Methods In this retrospective investigation, 314 consecutive who were diagnosed NSTEMI a tertiary center included. The SII was computed as neutrophils x platelets/lymphocytes. Based on increased values, we classified research sample into three tertile groups T1, T2, T3. defined primary outcomes. Results Patients T3 group had lower chances survive both periods compared those T2 T1 groups. independently related (HR: 1.001, 95% CI: 1.000–1.1003, p=0.038) 1.004, 1.002–1.006, p<0.001) according multivariable Cox regression models. To predict mortality, optimal >2174 80% sensitivity 85.4% specificity. When AUC values SII, neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte (PLR) assessed greatest (AUC: 0.862), followed by NLR 0.731) PLR 0.698). Additionally, combining traditional risk factors Charlson Comorbidity Index revealed significant improvement C-statistics. Conclusion might be first demonstrate that linked patients. Funding Acknowledgement Type funding sources: None.